iTunes 12.4.1 can be downloaded immediately from the Software Update mechanism in the Mac App Store.
This update addresses a number of problems where iTunes doesn't work as expected with VoiceOver. It also restores the option to Reset Plays and fixes the following issues:iTunes 12.4.1 comes just over two weeks after the release of iTunes 12.4, an update that introduced a revamped interface designed to be simpler, with the reintroduction of a sidebar for easier navigation and a redesigned media picker. It also featured safeguards to protect users from an issue that could cause music stored in iTunes to be deleted.
- Up Next may have unexpectedly played songs added together in the incorrect order.
- iTunes was prevented from crossfading between songs.