Apple's yearly developer conference should see iOS 8, OS X 10.10, and likely some hardware.
Many U.S. and Canadian Apple Retail Stores Opening Early for Black Friday Sales
Shoppers interested in going to Apple Stores as early as possible, on the only day of the year that Apple offers sale prices on its merchandise, should check Apple's Retail Store Locations page where special holiday hours are posted on each store's page. Some locations will be opening as early as 6AM.
Some retail stores in other countries have pop-ups as well, as many countries will see extended holiday hours as we move deeper into the holiday season.
In past years, Apple has offered discounts on iPads, iPods and some Mac models on Black Friday.